Author

Shane Donahue

Edward Via College of Osteopathic MedicineORCID 0009-0001-8708-3106Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

Bidyut K. MohantyiD· 3 shared Daniel E. RossiD· 3 shared David EagertoniD· 3 shared Olivia LewisiD· 3 shared Christopher Syed· 2 shared Levi DigginsiD· 2 shared Olivia McLeaniD· 2 shared Rachael D. BakeriD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiophysics

Bidyut K. MohantyORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 16, 2026

QuadCleave: Enzymatic cleavage and analysis of DNA G-quadruplexes.

Rachael D. Baker, Alaina Hrysikos, Olivia Lewis…·Bidyut K. Mohanty

QuadCleave provides an inexpensive, efficient method to validate G4-forming sequences and assess their repeat counts using two enzymes, with application to C9ORF72 in ALS and FTD.

DOI 10.64898/2026.05.15.725486

DNA methylationexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintJun 2, 2025

Thermally activated irreversible homogenization of G-quadruplexes in an ALS/FTD-associated nucleotide expansion

Daniel E. Ross, Olivia Lewis, Olivia McLean…·Bidyut K. Mohanty

This paper investigates thermally activated irreversible homogenization of G-quadruplexes in C9ORF72 hexanucleotide repeats, linking conformational changes to disease mechanisms.

1 citation

DNA methylationexperimental assay

𝕏 PostBluesky

BiophysicsBiophysical ReportsPeer-reviewedNov 27, 2024

Multiple factors regulate i-motif and G-quadruplex structures in vitro: analysis of repeated and non-repeated polyG/polyC clusters by circular dichroism

Levi Diggins, Daniel Ross, Sundeep Bhanot…·Bidyut K. Mohanty

This study uses circular dichroism to analyze how environmental factors and DNA sequences affect G-quadruplex and i-motif formation in vitro.

9 citations

DNA methylationexperimental assay

𝕏 PostBluesky