Bidyut K. Mohanty

QuadCleave provides an inexpensive, efficient method to validate G4-forming sequences and assess their repeat counts using two enzymes, with application to C9ORF72 in ALS and FTD.

This paper investigates thermally activated irreversible homogenization of G-quadruplexes in C9ORF72 hexanucleotide repeats, linking conformational changes to disease mechanisms.

This study uses circular dichroism to analyze how environmental factors and DNA sequences affect G-quadruplex and i-motif formation in vitro.

ExoChew generates single-stranded DNA libraries by enzymatically converting double-stranded DNA fragments, enabling genome-wide studies of protein-DNA interactions and DNA structures.