Fei Yang

ImmuneLens links transcriptional states and TCR clonotypes using disentangled multimodal learning to improve antigen-specificity prediction and reveal T cell heterogeneity in immunotherapy.

The paper curates noncanonical neoantigen-HLA pairs and develops predictive models, providing a public resource for neoantigen research and vaccine development.

scVar detects low-frequency somatic mutations in single-cell RNA sequencing data and integrates them with transcriptomic profiles to study tumor heterogeneity.