Author

Holly O’Shea

University at Buffalo, State University of New YorkORCID 0009-0001-9615-763XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Dongjun ShiniD· 2 shared Jaein Park· 2 shared Liwen LiiD· 2 shared Shin Teo JeoniD· 2 shared Soo‐Kyung LeeiD· 2 shared Camille F. Harrison· 1 shared Elise BrimbleiD· 1 shared HJ LeeiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersDevelopmental Biology

Dongjun ShinORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintDec 5, 2025

AAV-mediated neuronal expression of FOXG1 restores oligodendrocyte maturation, myelination, and hippocampal structure in mouse models of FOXG1 Syndrome

Jaein Park, Holly O’Shea, Shin Teo Jeon…·Soo‐Kyung Lee

This study shows that delivering FOXG1 to neurons via AAV vectors improves oligodendrocyte maturation, myelination, and hippocampal structure in mouse models of FOXG1 syndrome.

2 citations

mouseexperimental assay

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NeuroscienceNature CommunicationsPeer-reviewedMay 22, 2025

The patient-specific mouse model with Foxg1 frameshift mutation provides insights into the pathophysiology of FOXG1 syndrome

Shin Teo Jeon, Jaein Park, Ji Hwan Moon…·Soo‐Kyung Lee

This study creates a patient-specific mouse model with a Foxg1 frameshift mutation to investigate FOXG1 syndrome, revealing cellular and behavioral phenotypes and the role of the mutant protein fragment.

9 citationstop 4%

mouseexperimental assay

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