Author

Tina Gao

Albert Einstein College of MedicineORCID 0009-0001-9992-7425Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Approach:Bayesian inference· 1 Assay:GWAS summary statistics· 1 Research Focus:polygenic risk· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Nir BarzilaiiD· 3 shared Sofiya MilmaniD· 3 shared Zhengdong D. ZhangiD· 3 shared Jan VijgiD· 2 shared Jhih-Rong LiniD· 2 shared Alexander Y. MasloviD· 1 shared Amanat AliiD· 1 shared Cristina MontagnaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBioinformatics

Nir BarzilaiORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJul 1, 2026

Direct probabilistic quantification of mosaic loss of chromosome Y from sequencing data

Jhih-Rong Lin, Yoke‐Chen Chang, Alexander Y. Maslov…·Zhengdong D. Zhang

This paper introduces BaySeq-Y, a Bayesian method to directly quantify mosaic loss of chromosome Y from sequencing data, showing improved accuracy over existing methods.

DOI 10.64898/2026.06.26.734767

humanwhole-genome sequencing

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BiophysicsScientific ReportsPeer-reviewedMar 25, 2025

Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity

Amanat Ali, Zhengdong D. Zhang, Tina Gao…·Sofiya Milman

This study identifies two functional IGF-1 coding variants in centenarians that may contribute to exceptional longevity by impairing IGF-1R activity and reducing circulating IGF-1 levels.

8 citationstop 4%

humanwhole-exome sequencing

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Genetic & Genomic MedicineScientific ReportsPeer-reviewedAug 28, 2024

Polygenic prediction of human longevity on the supposition of pervasive pleiotropy

Mohammad Reza Jabalameli, Jhih-Rong Lin, Quanwei Zhang…·Zhengdong D. Zhang

This study develops a polygenic score to predict exceptional longevity by modeling pleiotropic genetic variants linked to aging-related traits, showing improved lifespan prediction and identifying potential drug targets.

3 citations

humanGWAS summary statistics

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