Jana Ruíz-Castro

Differential contribution of elastin and fibrillin-1 to the cardiovascular phenotype of a double heterozygous Marfan and Williams-Beuren syndrome mouse model

This study examines a double heterozygous mouse model of Marfan and Williams-Beuren syndromes, showing combined vascular and cardiac phenotypes related to elastin and fibrillin-1.

Allopurinol improves cardiovascular phenotypes of a mouse model for Williams-Beuren syndrome reducing redox stress

This study evaluates the effects of Allopurinol and Losartan on cardiovascular phenotypes in a mouse model of Williams-Beuren syndrome, finding that Allopurinol reduces blood pressure and improves cardiac pathology.