Author

Shan Zhang

National Institutes of HealthORCID 0009-0002-0732-7025Unclaimed ORCID profile · follow to get notified of new preprints

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Shan Zhang1 paper · Shenzhen University

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Biochemistry· 1

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

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Esam A. OrabiiD· 1 shared José D. Faraldo‐GómeziD· 1 shared Nathan A. BernhardtiD· 1 shared Robyn StixiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiochemistry

Esam A. OrabiORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivJul 25, 2024

Distinct mechanisms of inhibition of Kv2 potassium channels by tetraethylammonium and RY785

Shan Zhang, Robyn Stix, Esam A. Orabi…·José D. Faraldo‐Gómez

This paper uses molecular dynamics simulations to compare how RY785 and TEA inhibit Kv2.1 channels, showing RY785 stabilizes a semi-open gate state while TEA blocks the pore.

DOI 10.7554/elife.101855

structural biologymechanistic / dynamical model

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