Author

Brandon Emanuel León

University of MiamiORCID 0009-0002-1708-7563Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Asmita PathakiD· 2 shared Bruno ColoniD· 2 shared David B. LombardiD· 2 shared Defne BayıkiD· 2 shared Durga Prasad GannamediiD· 2 shared Erika CiervoiD· 2 shared Jonathan MitchelliD· 2 shared Michele CeccarelliiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Asmita PathakORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologyNature CancerPeer-reviewedJun 23, 2026

γ-aminobutyric acid receptor B signaling drives glioblastoma in females in an immune-dependent manner

Asmita Pathak, Sravya Palavalasa, Bruno Colon…·Defne Bayık

This study shows GABA receptor B signaling promotes GBM growth in females through immune mechanisms, with sex-specific effects on survival and treatment outcomes.

12 citationstop 1%

humanbulk RNA-seq

ImmunologybioRxivPreprintApr 3, 2026

Pharmacologic DPP-4 inhibition promotes CD8⁺ T cell metabolic fitness to enhance anti-tumor activity

Oriana Teran Pumar, Elton L VanNoy, Abigail Haffey…·Defne Bayık

This study shows that DPP-4 inhibition improves CD8+ T cell metabolism and anti-tumor activity in preclinical and clinical settings.

DOI 10.64898/2026.03.31.715681

mousehuman