In silico neuritogenesis model underpins mechanical interactionswith extracellular matrix as determinants of persistent axonal growthin stiffer microenvironments
Mathar Kravikass, Lars Bischof, Kristina Karandasheva, Federica Furlanetto, Pritha Dolai, Sven Falk, Marisa Karow, Katja Kobow, Ben Fabry, Vasily Zaburdaev
The paper presents an in silico model of neurite growth that simulates interactions with the extracellular matrix, showing that stiffer environments promote more persistent axonal growth.
bioRxiv · Mar 17, 2026 · PreprintNeuroscience