Mathar Kravikass

Not All Charges Are Equal: Side-Chain Chemistry Reshapes the Disordered Ensemble of α-synuclein

This paper shows that arginine substitutions, despite similar charge, compact α-synuclein more than lysine, accelerating amyloid formation and reshaping its disordered ensemble.

In silico model of axonal pathfinding during spinal cord regeneration in zebrafish larvae

The paper develops an agent-based model to simulate axonal growth during zebrafish spinal cord regeneration and shows it aligns with experimental imaging data.

In silico neuritogenesis model underpins mechanical interactionswith extracellular matrix as determinants of persistent axonal growthin stiffer microenvironments

The paper presents an in silico model of neurite growth that simulates interactions with the extracellular matrix, showing that stiffer environments promote more persistent axonal growth.

Aberrant formation of long-range projections across different neurodevelopmental disorders converges on molecular and cellular nexuses

The paper investigates how mutations in SOX11, MID1, and TCF4 affect neurite formation in neurodevelopmental disorders, revealing shared molecular and cellular mechanisms.