Marisa Karow

The paper presents an in silico model of neurite growth that simulates interactions with the extracellular matrix, showing that stiffer environments promote more persistent axonal growth.

This study shows that mechanical forces influence neural stem cell lineage decisions in human brain organoids through changes in molecular programs and cellular metabolism.

The paper investigates how mutations in SOX11, MID1, and TCF4 affect neurite formation in neurodevelopmental disorders, revealing shared molecular and cellular mechanisms.

The paper identifies the Feret diameter as a reliable quality marker for brain organoids and shows mesenchymal cells negatively impact organoid formation.

This study reprograms early cortical astroglia into neurons with parvalbumin-positive interneuron features using a modified Ascl1 protein.

The paper shows that reactivation of inactive X-chromosome alleles in female neural cells during differentiation enhances resilience to X-linked neurodevelopmental disorders.

The paper shows neurons and astrocytes in specific brain regions share transcriptional and epigenetic signatures, which are maintained even after reprogramming.

This study shows that forced Neurog2 expression in adult SEZ progenitors reprograms them to generate glutamatergic neurons, but not their postmitotic progeny.