Anti-phage defence systems are enriched in multidrug-resistant Pseudomonas aeruginosa
Lisa H Olijslager, Nadiia Pozhydaieva, Stan J. J. Brouns, Antoni P. A. Hendrickx, Pieter‐Jan Haas
The paper analyzes the defensome of Pseudomonas aeruginosa across clinical datasets, finding that multidrug-resistant isolates have more defence systems while cystic fibrosis isolates have fewer, with implications for phage therapy.
bioRxiv · Aug 18, 2026 · PreprintMicrobiology