Molecular BiologybioRxivPreprint
The cytosolic cysteinyl-tRNA synthetase is capable of regulating ATF4 translation independent of eIF2α phosphorylation state
Acer E. Xu, Jonathan S. Weissman
The paper identifies a novel pathway for ATF4 translation activation through CARS loss, independent of eIF2α phosphorylation and mTOR signaling.
DOI 10.1101/2024.12.23.630120