BiophysicsbioRxivPreprint
From Attraction to Repulsion: Omicron-Driven Rewiring of Nanobody Interfaces on the SARS-CoV-2 RBD
Mert Gölcük, Fareeda E. Abu-Juam, Derman Basturk…·Mert Gür
This study uses molecular dynamics simulations to analyze how Omicron mutations affect nanobody binding to the SARS-CoV-2 RBD, revealing structural changes and reduced binding stability.
DOI 10.1101/2025.07.18.665531