Author

Jack M Sendek

Yale UniversityORCID 0009-0002-2731-3296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alex J. Mora PaganiD· 1 shared Fadi G. AkariD· 1 shared Ilhan Gokhan· 1 shared Stuart G. CampbelliD· 1 shared Xia LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperPhysiology

Alex J. Mora PaganORCID

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1 paper

Recent·Most cited

Desmoplakin loss leads to PKC-dependent insertion of series sarcomeres and contractile dysfunction in cardiomyocytes

Ilhan Gokhan, Xia Li, Jack M Sendek, Alex J. Mora Pagan, Fadi G. Akar, Stuart G. Campbell

This study shows that desmoplakin loss causes PKC-dependent sarcomere shortening and contractile dysfunction in cardiomyocytes, leading to heart failure.

bioRxiv · May 15, 2025 · PreprintPhysiology