Palmitoylation of death receptor p75NTR contributes to Alzheimer's Disease progression by regulating APP trafficking and degradation
Yanchen Ma, Meng Xie, Carlos F. Ibáñez
This study shows that palmitoylation of p75NTR reduces its stability and APP trafficking to lysosomes, increasing Aβ accumulation and neuropathology in AD.
Alzheimer s Research & Therapy · Mar 27, 2026Peer-reviewedNeuroscience