Structural elucidation of the hexameric MmpS4-MmpL4 complex from Mycobacterium tuberculosis
Jennifer C. Earp, Nicolas P. Lichti, Alisa A. Garaeva, Virginia Meikle, Michael Niederweis, Markus A. Seeger
The paper determines the cryo-EM structure of the hexameric MmpS4-MmpL4 complex from Mycobacterium tuberculosis, revealing the coiled-coil domain and conformational changes compared to the monomer.
bioRxiv · Jan 8, 2026 · PreprintBiochemistry