MicrobiologyVirusesPeer-reviewed
Global Metabolomic Analysis of Lytic KSHV Infection: Induced Host Nucleotide Metabolism is Required for Infectious Virus Production
Fatima Hisam, Emma A Winn, Spandan Mukherjee…·Erica L. Sanchez
This study shows that inhibiting nucleotide metabolism with methotrexate reduces KSHV lytic infection and virion production, suggesting a therapeutic target for gammaherpesviruses.
DOI 10.3390/v18080877