Erica L. Sanchez

vGPCR-mediated ANO1 Modulation of Apoptosis Regulates Lytic KSHV Infection

This paper identifies ANO1 as a host factor induced by vGPCR that suppresses apoptosis and modulates KSHV lytic replication, linking cell survival to viral pathogenesis.

Global Metabolomic Analysis of Lytic KSHV Infection: Induced Host Nucleotide Metabolism is Required for Infectious Virus Production

This study shows that inhibiting nucleotide metabolism with methotrexate reduces KSHV lytic infection and virion production, suggesting a therapeutic target for gammaherpesviruses.

An oral fentanyl self-administration model reveals dissociable escalation and relapse phenotypes in outbred vs inbred mice

This paper develops an oral fentanyl self-administration model in mice to study escalation and relapse phenotypes, finding genetic background influences on these behaviors.

Impact of Neurons on Group B Streptococcus Interactions at the Blood Brain Barrier

This study shows that neuronal-endothelial communication enhances blood-brain barrier resistance to Group B Streptococcus (GBS) infection by reducing bacterial adherence and invasion.

Global Lipidomic Analysis of Lytic KSHV Infection: The Lipid Chaperone FABP4 is Required for Maximal Infectious Virion Production

LANA-dependent Interaction of Host Factors DAXX and BRD4 Impact KSHV Lytic Replication

This paper identifies DAXX and BRD4 as LANA-interacting host factors that support KSHV latency, while LIG3 is required for lytic reactivation, revealing their roles in viral replication.

TLR4+ Dermal fibroblasts induce acute and transitional pain states

This study shows that TLR4+ dermal fibroblasts induce acute and transitional pain states in mice through inflammatory and calcium signaling mechanisms.