Author

Alisa Kumbara

University of VeronaORCID 0009-0002-3899-3928Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Manuel TognoniD· 2 shared Rosalba GiugnoiD· 2 shared Andrea BettiiD· 1 shared Arianna FontanesiiD· 1 shared Giulia CaroneiD· 1 shared Lorenzo RuggeriiD· 1 shared Luca PinelloiD· 1 shared Nicola BombieriiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersBioinformatics

Manuel TognonORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 26, 2026

CRISPR-HAWK: Haplotype- and Variant-aware Guide Design Toolkit for CRISPR-Cas

Alisa Kumbara, Manuel Tognon, Giulia Carone…·Luca Pinello

CRISPR-HAWK identifies genetic variants affecting CRISPR guide performance across diverse populations, revealing that 82.5% of therapeutic guides are impacted by variants.

DOI 10.64898/2025.12.27.696698

humanwhole-genome sequencing

BioinformaticsbioRxivPreprintMar 20, 2025

Benchmarking PWM and SVM-based Models for Transcription Factor Binding Site Prediction: A Comparative Analysis on Synthetic and Biological Data

Manuel Tognon, Alisa Kumbara, Andrea Betti…·Rosalba Giugno

This study benchmarks PWM and SVM-based models for TFBS prediction using synthetic and biological data, highlighting their strengths and limitations under different conditions.

1 citation

humanChIP-seq