Author

Yaoan Leng

Boston UniversityORCID 0009-0002-3957-5250Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:software / tool· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:metagenomics· 1

Frequent Co-Authors

Sean LuiD· 2 shared William Evan JohnsoniD· 2 shared Alzheimer’s Disease Neuroimaging Initiative· 1 shared Aubrey R. Odom-MabeyiD· 1 shared Avi ShahiD· 1 shared Evan Holmes· 1 shared Howard Fan· 1 shared Jessica McClintockiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioinformatics

Sean LuORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 13, 2026

Reproducible Tools and Enhanced Computational Workflows for Batch Effect Evaluation of High-Throughput Data Using BatchQC

Jessica McClintock, Jiwei Zhang, Xinzhou Ge…·Alzheimer’s Disease Neuroimaging Initiative

The paper introduces BatchQC, an R package for assessing and correcting batch effects in high-throughput data with reproducible tools and workflows.

1 citation

statistical modelbenchmark study

𝕏 PostBluesky

BioinformaticsbioRxivPreprintAug 29, 2025

MetaScope: A High-Resolution Framework for Species-Level 16S Metataxonomic Classification

Sean Lu, Aubrey R. Odom-Mabey, Avi Shah…·William Evan Johnson

MetaScope improves species-level classification of microbial communities using 16S rRNA data, achieving higher accuracy than existing tools like QIIME2 and DADA2.

DOI 10.1101/2025.08.29.673160

metagenomicsstatistical model

𝕏 PostBluesky