Priyam Narain

The paper identifies distinct transcriptional changes in habenular cell subtypes associated with different depressive-like behavioural phenotypes in mice.

The paper identifies Pde10a as a regulator of neuronal excitability in SCN neurons, showing its rhythmic expression drives a depolarized silent state.

The paper identifies nighttime-specific gene expression changes in the habenula and suprachiasmatic nucleus of stress-resilient mice compared to stress-naive mice.

This study shows that chronic social stress in mice dampens core body temperature and thermosensitive gene rhythms in the lateral habenula, with faster recovery of temperature rhythms in resilient mice.

This study shows that stress-susceptible mice have blunted diurnal firing in LHb-DRN projections and slower photoentrainment, while resilient mice maintain normal rhythms and faster entrainment.