BiophysicsbioRxivPreprint
Impact of the Microtubule Cytoskeleton on Insulin Transport in Beta Cells: A 3D Computational Study
T.‐H. Thieu, William R. Holmes
This paper develops a 3D computational model to study how the dense microtubule network in beta cells affects insulin vesicle mobility and secretion, finding that caging by microtubules impairs vesicle movement and reduces insulin availability.