EGR1 drives sex-differences in glioblastoma tumorigenicity
Thamara J. Abouantoun, Lorida Llaci, Jason P. Wong, Lihua Yang, Nicole M. Warrington, Lloyd Tripp, Jingqin Rosy Luo, Brian D. Muegge, Joshua B. Rubin, Robi David Mitra
This study identifies EGR1 as a key driver of sex differences in glioblastoma tumorigenicity, showing it mediates survival and treatment response differences between males and females.
bioRxiv · May 16, 2025 · PreprintCancer Biology