A pan-MHC reference graph with 246 fully contiguous phased sequences
Liza Huijse, Solomon M. Adams, Joshua N. Burton, Julianne K. David, Russell Julian, Galit Meshulam-Simon, Harry Mickalide, Bersabeh D. Tafesse, Verónica Calonga‐Solís, Ivan Rodrigo Wolf, Ashby J. Morrison, Danillo G. Augusto, Solomon Endlich
The paper creates a pan-MHC reference graph with 246 fully contiguous phased sequences, improving variant calling accuracy and population diversity representation.
bioRxiv · Sep 1, 2023 · PreprintGenomics