Systems BiologybioRxivPreprint
Molecular mechanisms of heart field specific cardiomyoscytedifferentiation- a computational modeling approach
Georgios Argyris, Ricco A Zeegelaar, Janine N. Post
The paper develops a Boolean gene regulatory network model to simulate cardiomyocyte differentiation into ventricular or atrial types, validated by reproducing known knockouts and aligning with marker gene expression.
DOI 10.1101/2024.12.19.629328