Janine N. Post

Nuclear Factor I genes drive chondrogenic cell-fate commitment

The paper maps chondrogenic cell-fate trajectories in hiPSCs using scRNA-seq and scATAC-seq, identifying NFIA and NFIB as key regulators driving chondrogenic commitment.

DANSE: a pipeline for dynamic modelling of time-series multi-omics data

DANSE models time-series multi-omics data to identify key transcription factors driving biological processes, using iPSC differentiation datasets as examples.

Molecular mechanisms of heart field specific cardiomyoscytedifferentiation- a computational modeling approach

The paper develops a Boolean gene regulatory network model to simulate cardiomyocyte differentiation into ventricular or atrial types, validated by reproducing known knockouts and aligning with marker gene expression.

Mapping SOX9 transcriptional dynamics during multi-lineage differentiation of human mesenchymal stem cells

The paper investigates SOX9 transcriptional dynamics in human mesenchymal stem cells during differentiation into chondrogenic, osteogenic, and adipogenic lineages, revealing subpopulations and donor-specific differences.