Glioblastoma initiation, migration, and cell types are regulated by core bHLH transcription factors ASCL1 and OLIG2
Bianca L. Myers, Kathryn J. Brayer, Luis E. Paez-Beltran, Matthew S. Keith, Hideaki Suzuki, Jessie Newville, Rebekka H. Anderson, Yunee Lo, Conner M. Mertz, Rahul Krishna Kollipara, Mark D. Borromeo, Robert M. Bachoo, Jane E. B. Johnson, Tou Yia Vue
This study shows ASCL1 and OLIG2 regulate glioblastoma initiation, migration, and cell types through their dynamic interactions and target gene regulation.
bioRxiv · Sep 30, 2023 · PreprintNeuroscience