Kathryn J. Brayer

Multi-Omic and Spatial Profiling Defines Outcome-Associated Tumor States in Head and Neck Adenoid Cystic Carcinoma

The paper integrates multi-omic and spatial data from HNACC tumors to identify outcome-associated tumor states, finding that aggressive tumors adopt a MYC/E2F-driven luminal state and develop a four-gene classifier for survival prediction.

Illuminating the renal response to pH stress with single-nucleus RNA sequencing

This study uses single-nucleus RNA sequencing to investigate sex-specific transcriptional responses of the kidney to acidosis and alkalosis in mice.

Gene-Expression Programs in Salivary Gland Adenoid Cystic Carcinoma Analyzed Using Single-Cell and Spatial Transcriptomics

This study uses single-cell and spatial transcriptomics to analyze gene expression in salivary gland adenoid cystic carcinoma, revealing tumor heterogeneity, molecular interactions, and potential therapeutic targets.

Identification of host lncRNAs that impact Venezuelan equine encephalitis virus replication

The paper identifies lncRNAs that influence VEEV replication in mouse astrocytes, showing that suppressing Snhg15 increases viral replication and affects antiviral gene expression.

Glioblastoma initiation, migration, and cell types are regulated by core bHLH transcription factors ASCL1 and OLIG2

This study shows ASCL1 and OLIG2 regulate glioblastoma initiation, migration, and cell types through their dynamic interactions and target gene regulation.