Author

Qing Luan

University of Notre DameORCID 0009-0002-6286-291XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Patricia L. ClarkiD· 2 shared James C. GumbartiD· 1 shared Lan YangiD· 1 shared Michael C. BaxaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiophysics

Patricia L. ClarkORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 22, 2026

Autotransporter folding avoids a kinetic trap during vectorial translocation across the bacterial outer membrane

Lan Yang, Qing Luan, Michael C. Baxa…·James C. Gumbart

The paper explains how autotransporter proteins avoid a kinetic trap during secretion by using a computational framework to reveal hidden conformational states.

DOI 10.64898/2026.08.22.746429

bacteria (other)protein structure

𝕏 PostBluesky

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedJul 30, 2025

Discovery of an on-pathway protein folding intermediate illuminates the kinetic competition between folding and misfolding

Qing Luan, Patricia L. Clark

This study identifies an on-pathway intermediate in the folding of a large protein, revealing a two-step folding mechanism and its role in navigating kinetic competition between folding and misfolding.

5 citations

experimental assayprotein folding & dynamics

𝕏 PostBluesky