Tatiane Macedo Silva

Jumonji-C demethylase 2 interacts with a nucleosome component to modulate chromatin state in Plasmodium falciparum

This study shows that PfJmjC2 interacts with histone H2A to modulate chromatin structure in P. falciparum, affecting nucleosome stability and epigenetic balance without altering var gene transcription.

Nutrient stress dramatically increases malaria parasite clag2 copy number to increase host cell permeability and enable pathogen survival

The paper shows that malaria parasites increase clag2 copy number under nutrient stress to enhance host cell permeability and survival.