Author

Dennis Mewis

ORCID 0009-0002-6901-901XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Anika JaekeliD· 2 shared Germo Gericke· 2 shared Manuel Sturzbecher‐Hoehne· 2 shared Marion Huber· 2 shared Prachi Bharat DesaiiD· 2 shared Manfred Ruediger· 1 shared Nicolas ChouiniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Anika JaekelORCID

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2 papers

Recent·Most cited

Comparable daughter radionuclide redistribution with superior tumor absorbed dose of the SSTR2 antagonist Ac-DOTA-TATE

Prachi Bharat Desai, Marion Huber, Dennis Mewis, Nicolas Chouin, Manuel Sturzbecher‐Hoehne, Germo Gericke, Anika Jaekel

This study compares tumor absorbed dose and daughter radionuclide redistribution between SSTR2 antagonist and agonist radioligands, finding superior tumor dose for the antagonist despite minimal internalization.

bioRxiv · Mar 18, 2026 · PreprintCancer Biology

Ac-DOTA-TATE in SSTR2-positive tumor models

Prachi Bharat Desai, Dennis Mewis, Marion Huber, Manuel Sturzbecher‐Hoehne, Manfred Ruediger, Germo Gericke, Anika Jaekel

This study compares the therapeutic efficacy of SSO110 radiolabeled with different radionuclides in SSTR2-positive tumor models, finding that [225Ac]Ac-SSO110 shows the highest anti-tumor activity.

bioRxiv · Mar 14, 2026 · PreprintCancer Biology