A Reproducible Fetal Lamb Model of Complex Gastroschisis with Temporal Characterization of Bowel Changes
Tomohiro Arai, Michael Anthony Belfort, David Basurto, Marianna Scuglia, Kanokwaroon Watananirun, Wasinee Tianthong, Tom Bleeser, Marta Grinza, Simen Vergote, Emma Van den Eede, Michaël Aertsen, Bethany Fisher, Alex Menys, Theo Thijs, Inge Depoortere, , Luc Joyeux
This paper establishes a fetal lamb model of complex gastroschisis, showing it reproducibly induces structural and functional bowel changes at term, with higher incidence at later post-induction intervals.
bioRxiv · Mar 27, 2026 · PreprintDevelopmental Biology