NeurosciencePLOS PathogensPeer-reviewed
A self-complementary recombinant adeno-associated virus vector coding for an anchorless prion protein carrying the G127V mutation extends survival in a rodent prion disease model
Thomas Zerbes, Claire E. Verkuyl, Cunjie Zhang…·Gerold Schmitt‐Ulms
This paper demonstrates that delivering a protective prion protein variant via gene therapy extends survival in a prion disease mouse model.
DOI 10.1371/journal.ppat.1014124