Mariam Museridze

This paper analyzes the declining representation of model organism research in scientific literature over the last three decades, noting a shift toward applied research and potential impacts on life sciences.

The paper shows that enhancer sequences for the Drosophila yellow gene are entangled and non-modular, with overlapping regulatory information and specific core segments driving independent activities.

The paper quantifies the spatial activity of a Drosophila enhancer through sequence mutagenesis and image analysis, revealing dense regulatory information and novel regulatory logic.