BioinformaticsbioRxivPreprint
Multimodal physical evidence uncovers interpretable gene regulatory networks for perturbation prediction
Zhiwen Yang, Sikai Huang, Ge Bai…·Stan Z. Li
The paper introduces VitaGRN, a multimodal biophysical framework that predicts perturbation responses and uncovers non-canonical regulatory mechanisms, demonstrating robust generalization across cell lines and factors.
DOI 10.64898/2026.06.05.729520