BioinformaticsbioRxivPreprint
Reverse-engineering B-Arrestin Bias in the d-Opioid Receptor
Tomasz Maciej Stępniewski, Manel Zeghal, Istvan Szabo…·Jana Selent
The paper uses molecular dynamics simulations to study signaling bias in the delta-opioid receptor, identifying structural determinants of beta-arrestin recruitment and demonstrating how mutations can reshape signaling profiles.
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