Author

Chanukya Nanduru

ORCID 0009-0003-3716-0331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Antarip HalderiD· 1 shared Kruthika AvadhaniiD· 1 shared Kumari SoniyaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperBiophysics

Antarip HalderORCID

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1 paper

Recent·Most cited

Selective Activation of GPCRs: Molecular Dynamics Shows Siponimod Binds but Fails to Activate S1PR2 Unlike S1PR1

Kumari Soniya, Kruthika Avadhani, Chanukya Nanduru, Antarip Halder

This study uses molecular dynamics to show that Siponimod binds both S1PR1 and S1PR2 but only activates S1PR1 by inducing conformational changes absent in S1PR2.

Journal of Chemical Information and Modeling · Dec 4, 2025Peer-reviewedBiophysics