Kiersten S. Campbell

This study identifies and validates serum protein biomarkers for Niemann-Pick disease, type C1, showing correlations with disease severity and response to therapy.

MOSAIC identifies driver mutations in cancer by accounting for patient subgroup heterogeneity in mutual exclusivity analysis, improving detection of subgroup-specific patterns.

The paper uses integrated bulk, single-cell, and spatial RNA-seq to uncover the timeline of osteogenic transcriptional programming in embryonic palate development, identifying novel genes and spatial expression patterns involved in palatal fusion.