Daniela Marta Roth

Bilayer FTY720-nanofiber scaffolds promote complete oral wound closure in a mouse model by modulating pro-regenerative immune and stromal cells.

The paper identifies tendon-associated gene expression as a key factor in mid-palatal suture establishment and shows similarities with cranial suture biology.

This study investigates the role of Dkk2 in palatogenesis using Pax9-/- mouse models and spatial multiomics data, revealing its spatial relationship with osteogenic populations.

The paper uses integrated bulk, single-cell, and spatial RNA-seq to uncover the timeline of osteogenic transcriptional programming in embryonic palate development, identifying novel genes and spatial expression patterns involved in palatal fusion.

The paper develops a process-centered multivariate genotype-phenotype approach to analyze craniofacial shape variation in mice, linking gene sets to shape axes and predicting phenotypic effects beyond shape.