BiophysicsbioRxivPreprint
Phosphorylation and pocket-binding ligands rewire the coupled networks in multidomain protein condensate
Yu Cao, Jinyu Chen, Xiakun Chu
This study shows how phosphorylation and pocket-binding ligands regulate condensate organization in multidomain proteins like HDAC6 through distinct electrostatic and interaction mechanisms.
DOI 10.64898/2026.08.07.743494