Author

Jack Hung-Sen Lai

Tufts UniversityORCID 0009-0003-4566-1961Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alfred Lewis GoldbergiD· 1 shared Bertrand D. E. RaynaliD· 1 shared Diego F. GautoiD· 1 shared Dmitry A. SemchonokiD· 1 shared Eric J. RubiniD· 1 shared Hugo FragaiD· 1 shared Katharina WeinhäupliD· 1 shared M. Teresa Bueno-CarrascoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alfred Lewis GoldbergORCID

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1 paper

Recent·Most cited

BiochemistryCell ReportsPeer-reviewedMay 30, 2026

Activation Mechanism and Structural Assembly of the Mycobacterium tuberculosis ClpP1P2 Protease and Its Associated ATPases.

Katharina Weinhäupl, Tatos N. Akopian, Dmitry A. Semchonok…·Hugo Fraga

This study identifies trehalose as an activator of ClpC1P1P2 and ClpXP1P2 protease complexes in Mycobacterium tuberculosis, revealing a new mechanism for in vivo activation without the need for peptide activators.

7 citationstop 3%

bacteria (other)experimental assay

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