Author

Han Guo

ORCID 0009-0003-5604-3085Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:deep learning· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Eric Poe XingiD· 2 shared Pengtao XieiD· 2 shared Xingyi ChengiD· 2 shared Youwei LiangiD· 2 shared Caleb N. EllingtoniD· 1 shared Changjiang Gou· 1 shared Jing GongiD· 1 shared Le SongiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioinformatics

Eric Poe XingORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintApr 30, 2026

Harnessing AI to Build Virtual Cells

Xingyi Cheng, Pan Li, Han Guo…·Eric Poe Xing

This paper introduces VCHarness, an AI system that automatically builds perturbation-response models for virtual cells, outperforming manual methods and reducing development time.

DOI 10.64898/2026.04.11.717183

deep learningstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 29, 2026

Using AI to Build AI: AIDO.Builder Enables Autonomous Machine Learning Model Building for Biomedicine

Han Guo, Youwei Liang, Xingyi Cheng…·Eric P. Xing

AIDO.Builder automates biomedical model development by generating executable pipelines, selecting strategies, and iteratively refining models without manual intervention.

DOI 10.64898/2026.04.20.719735

deep learningstatistical model

𝕏 PostBluesky