Author

Leslie Arthur Smith

University of FloridaORCID 0009-0003-6375-7158Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Kiley S. GraimiD· 2 shared Andrew H. Bertrand· 1 shared Beulah Augustin· 1 shared Bria Synae SmithiD· 1 shared Charlotte HopsoniD· 1 shared Emilio B. Cagmat· 1 shared Faheem W. GuirgisiD· 1 shared James A. CahilliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioinformatics

Kiley S. GraimORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 28, 2026

Deciphering sepsis molecular subtypes using large-scale data to identify subtype-specific drug repurposing

Leslie Arthur Smith, Beulah Augustin, Vinitha Jacob…·Kiley S. Graim

This paper identifies four molecular subtypes of sepsis using transcriptomic data and proposes subtype-specific drug repurposing opportunities, including potential therapies for high mortality subtypes.

DOI 10.64898/2026.03.28.714506

humanbulk RNA-seq

BioinformaticsbioRxivPreprintMay 18, 2026

The Paipu framework enables creation of a large-scale mammalian cancer transcriptomics atlas

Bria Synae Smith, Leslie Arthur Smith, Ji‐Hyun Lee…·Kiley S. Graim

The paper introduces Paipu, a pipeline for creating a multi-species cancer transcriptomics atlas by harmonizing RNA-seq data from the SRA.

DOI 10.64898/2026.05.14.725161

mousehuman