BioengineeringMolecular Therapy — Methods & Clinical DevelopmentPeer-reviewed
Unlocking DOE potential selecting the most appropriate design for rAAV optimization
Konstantina Tzimou, David Catalán-Tatjer, Lars Keld Nielsen, Jesús Lavado‐García
This study compares four DOE methods to optimize rAAV production by determining optimal plasmid and reagent ratios, finding that mixture design with face-centered central composite design performs best.
14 citations