Author

Aleksandra Gavrilova

Denison UniversityORCID 0009-0003-9069-0999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

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Nizhum RahmaniD· 1 shared Trachette Levon JacksoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperCancer Biology

Nizhum RahmanORCID

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1 paper

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Cancer BiologyJournal of Theoretical BiologyPeer-reviewedJun 18, 2026

Phenotypic Plasticity and Competition Shape Therapy Sequencing in HER2+/HER2- Breast Cancer: A Mathematical Framework

Aleksandra Gavrilova, Trachette Levon Jackson, Nizhum Rahman

The paper develops a mathematical model to study how phenotypic plasticity and competition between HER2+ and HER2- cells affect treatment outcomes in breast cancer, showing that treatment order and intensity influence long-term tumour composition.

DOI 10.1016/j.jtbi.2026.112533

humanmechanistic / dynamical model

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