Stimulation of locus coeruleus inputs to the frontal cortex in mice induces cell type-specific expression of the Apoe gene
Genevieve E. Craig, Lizbeth Ramos, Samuel R. Essig, Nicholas J. Eagles, Andrew E. Jaffe, Keri Martinowich, Henry L. Hallock
The paper stimulates locus coeruleus inputs to the frontal cortex in mice and finds cell type-specific Apoe gene expression, particularly in GABAergic neurons, with sex-dependent effects.
bioRxiv · Jul 22, 2024 · PreprintGenetics