NeuroscienceProceedings of the National Academy of SciencesPeer-reviewed
Selective loss of Primary Cilia and Neurotrophic Signaling in G51D alpha-Synuclein Mice Highlights a Common Pathway to Parkinsons Disease
Yu‐En Lin, Ebsy Jaimon, Young Doo Kim…·Suzanne R. Pfeffer
The paper shows that G51D alpha-synuclein mice exhibit loss of primary cilia and neurotrophic signaling in specific brain regions, linking ciliary dysfunction to Parkinson's disease pathology.