Developmental BiologybioRxivPreprint
A kidney specific mouse model to study the effects of in vivo induction of Yamanaka factors
Katharina Lemberg, Gijs A. C. Franken, Korbinian Maria Riedhammer…·Friedhelm Hildebrandt
This study investigates the effects of in vivo induction of Yamanaka factors (OKS) in a kidney-specific mouse model to enhance tissue repair after acute kidney injury, finding that while feasible, it carries risks of oncogenic transformation.
DOI 10.1101/2025.08.30.672899