Author

Denis Sidorenko

Hong Kong Science and Technology Parks CorporationORCID 0009-0004-0571-5192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 4

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:proteomics· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Alex A. ZhavoronkoviD· 4 shared Alexander M. AliperiD· 4 shared Diana ZagirovaiD· 4 shared Fedor GalkiniD· 4 shared Vladimir NaumoviD· 4 shared Stefan PushkoviD· 3 shared Khadija M. AlawiiD· 2 shared Vladimir AladinskiyiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersBioinformatics

Alex A. ZhavoronkovORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Longevity Bench: Are SotA LLMs ready for aging research?

Alex A. Zhavoronkov, Denis Sidorenko, Vladimir Naumov, Stefan Pushkov, Diana Zagirova, Vladimir Aladinskiy, Derya Unutmaz, Alexander M. Aliper, Fedor Galkin

The paper introduces LongevityBench, a benchmark to evaluate LLMs' ability to understand aging biology and predict age-related outcomes from biodata.

bioRxiv · Apr 15, 2026 · PreprintBioinformatics

The End of Aging Clocks: Training Foundation Models to Reason in Aging and Longevity

Alex A. Zhavoronkov, Vladimir Aladinskiy, Alex Aliper, Zulfat Miftahutdinov, Mathieu Reymond, Vladimir Naumov, Diana Zagirova, Stefan Pushkov, Denis Sidorenko, Rim Shayakhmetov, Fedor Galkin

The paper introduces Longevity-LLM, a foundation model fine-tuned on aging-related data, achieving high performance in age prediction and proteomic profile generation across multiple modalities.

bioRxiv · Mar 30, 2026 · PreprintBioinformatics

DORA AI Scientist: Multi-agent Virtual Research Team for Scientific Exploration Discovery and Automated Report Generation

Vladimir Naumov, Diana Zagirova, Sha Lin, Yupeng Xie, Wenhao Gou, Anatoly Urban, Nina Tikhonova, Khadija M. Alawi, Mike Durymanov, Fedor Galkin, Shan Chen, Denis Sidorenko, Mike Korzinkin, Morten Scheibye‐Knudsen, Alán Aspuru‐Guzik, , Alex A. Zhavoronkov

DORA AI Scientist automates scientific research tasks and report generation using multi-agent AI systems and LLMs, reducing manuscript preparation time and enabling more focus on discovery.

bioRxiv · Mar 6, 2025 · PreprintBioinformatics

Precious3GPT: Multimodal Multi-Species Multi-Omics Multi-Tissue Transformer for Aging Research and Drug Discovery

Fedor Galkin, Vladimir Naumov, Stefan Pushkov, Denis Sidorenko, Anatoly S. Urban, Diana Zagirova, Khadija M. Alawi, Alex Aliper, Ruslan Gumerov, Aleksandr Kalashnikov, Sabina Mukba, Aleksandra Pogorelskaya, Feng Ren, Anastasia Shneyderman, Qiuqiong Tang, , Alex A. Zhavoronkov

This paper introduces P3GPT, a multimodal transformer model for aging research and drug discovery that performs multiple tasks across species, tissues, and omics data.

bioRxiv · Jul 25, 2024 · PreprintBioinformatics